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Effect of methylmalonate on ketone body metabolism in developing rat brain

Mulchand S. Patel, Oliver E. Owen, Cindy Raefsky

Journal:

Life Sciences

Année:

1976

Langue:

english

Fichier:

PDF, 359 KB

english, 1976

Insulin receptors in developing rat liver: Acquisition of down regulation in the immediate postnatal period

Angela M. Caliendo, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1983

Langue:

english

Fichier:

PDF, 949 KB

english, 1983

Dihydrolipoamide dehydrogenase: Functional similarities and divergent evolution of the pyridine nucleotide-disulfide oxidoreductases

Donna J. Carothers, Gabriel Pons, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1989

Langue:

english

Fichier:

PDF, 1.25 MB

english, 1989

Fatty acid synthesis by human adipose tissue

Mulchand S. Patel, Oliver E. Owen, Leonard I. Goldman, Richard W. Hanson

Journal:

Metabolism

Année:

1975

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1975

Substrate, hormone, and temperature responses in males and females to a common breakfast

Oliver E. Owen, Maria A. Mozzoli, Guenther Boden, Mulchand S. Patel, George A. Reichard Jr., Volker Trapp, Charles R. Shuman, Philip Felig

Journal:

Metabolism

Année:

1980

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1980

[Part 2: Biological Sciences] || Ketone-Body Metabolism in Glioma and Neuroblastoma Cells

Mulchand S. Patel, Joseph J. Russell and Howard Gershman

Journal:

Proceedings of the National Academy of Sciences

Année:

1981

Langue:

english

Fichier:

PDF, 805 KB

english, 1981

[Oxidative Stress and Disease] Lipoic Acid Volume 20080652 (Energy Production, Antioxidant Activity and Health Effects) || Pharmacokinetics, Metabolism, and Renal Excretion of Alpha-Lipoic Acid and Its Metabolites in Humans

Patel, Mulchand, Packer, Lester

Année:

2008

Langue:

english

Fichier:

PDF, 626 KB

english, 2008

Acetyl-CoA production from pyruvate is not necessary for preservation of myelin

Della-Flora Nunes, Gustavo, Mueller, Lauren, Silvestri, Nicholas, Patel, Mulchand S., Wrabetz, Lawrence, Feltri, M. Laura, Poitelon, Yannick

Journal:

Glia

Année:

2017

Langue:

english

Fichier:

PDF, 2.39 MB

english, 2017

Three new mutations of the pyruvate dehydrogenase alpha subunit: A point mutation (M181V), 3 bp deletion (-R282), and 16 bp insertion/frameshift (K358SVS→TVDQS)

Amporn Tripatara, Douglas S. Kerr, Marilyn M. Lusk, Madhu Kolli, Jie Tan, Mulchand S. Patel

Journal:

Human Mutation

Année:

1996

Langue:

english

Fichier:

PDF, 305 KB

english, 1996

Mutations in the X-linked pyruvate dehydrogenase (E1) α subunit gene (PDHA1) in patients with a pyruvate dehydrogenase complex deficiency

Willy Lissens, Linda De Meirleir, Sara Seneca, Inge Liebaers, Garry K. Brown, Ruth M. Brown, Michinori Ito, Etsuo Naito, Yasuhiro Kuroda, Douglas S. Kerr, Isaiah D. Wexler, Mulchand S. Patel, Brian H.

Journal:

Human Mutation

Année:

2000

Langue:

english

Fichier:

PDF, 290 KB

english, 2000

The biochemistry of the pyruvate dehydrogenase complex

Mulchand S. Patel, Lioubov G. Korotchkina

Journal:

Biochemistry and Molecular Biology Education

Année:

2003

Langue:

english

Fichier:

PDF, 556 KB

english, 2003

Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons

Nader D. Halim, Thomas Mcfate, Ahmed Mohyeldin, Peter Okagaki, Lioubov G. Korotchkina, Mulchand S. Patel, Nam Ho Jeoung, Robert A. Harris, Michael J. Schell, Ajay Verma

Journal:

Glia

Année:

2010

Langue:

english

Fichier:

PDF, 332 KB

english, 2010

Effects of maternal dietary protein content on cerebral ketone body-metabolizing enzymes in the progeny of rats

Juliet John, Mulchand S. Patel, Shailaja D. Telang

Journal:

The Journal of Nutritional Biochemistry

Année:

1991

Langue:

english

Fichier:

PDF, 528 KB

english, 1991

Alterations in hepatic lipogenic capacity in rat pups artificially reared on a milk-substitute formula high in carbohydrate or medium-chain triacylglycerides

Bhargava K. Hiremagalur, Gary L. Johanning, Satish C. Kalhan, Mulchand S. Patel

Journal:

The Journal of Nutritional Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 749 KB

english, 1992

Alteration of enzymes of hepatic glycerolipid synthesis in artificially reared rat pups fed high carbohydrate and high fat diets

Rosalind A. Coleman, Bhargaya K. Hiremagalur, Jayne Trachman, Elaine S.-G. Bardes, Prema Rao, Mulchand S. Patel

Journal:

The Journal of Nutritional Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 580 KB

english, 1992

Acetylphosphinate is the most potent mechanism-based substrate-like inhibitor of both the human and Escherichia coli pyruvate dehydrogenase components of the pyruvate dehydrogenase complex

Natalia S. Nemeria, Lioubov G. Korotchkina, Sumit Chakraborty, Mulchand S. Patel, Frank Jordan

Journal:

Bioorganic Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 537 KB

english, 2006

Molecular adaptations in islets from neonatal rats reared artificially on a high carbohydrate milk formula

Malathi Srinivasan, Fei Song, Ravikumar Aalinkeel, Mulchand S. Patel

Journal:

The Journal of Nutritional Biochemistry

Année:

2001

Langue:

english

Fichier:

PDF, 352 KB

english, 2001

Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity

Peter Klivenyi, Anatoly A. Starkov, Noel Y. Calingasan, Gabrielle Gardian, Susan E. Browne, Lichuan Yang, Parvesh Bubber, Gary E. Gibson, Mulchand S. Patel, M. Flint Beal

Journal:

Journal of Neurochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 303 KB

english, 2004

A structural model for human dihydrolipoamide dehydrogenase

Joyce E. Jentoft, Menachem Shoham, Darren Hurst, Mulchand S. Patel

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1992

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1992

Successful TAT-mediated enzyme replacement therapy in a mouse model of mitochondrial E3 deficiency

Matan Rapoport, Lina Salman, Ofra Sabag, Mulchand S. Patel, Haya Lorberboum-Galski

Journal:

Journal of Molecular Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 343 KB

english, 2011

Brain MR Imaging and Proton MR Spectroscopy in Female Mice with Pyruvate Dehydrogenase Complex Deficiency

Lioudmila Pliss, Richard Mazurchuk, Joseph A. Spernyak, Mulchand S. Patel

Journal:

Neurochemical Research

Année:

2007

Langue:

english

Fichier:

PDF, 378 KB

english, 2007

Liver-Specific Pyruvate Dehydrogenase Complex Deficiency Upregulates Lipogenesis in Adipose Tissue and Improves Peripheral Insulin Sensitivity

Cheol Soo Choi, Pushpankur Ghoshal, Malathi Srinivasan, Sheene Kim, Gary Cline, Mulchand S. Patel

Journal:

Lipids

Année:

2010

Langue:

english

Fichier:

PDF, 361 KB

english, 2010

Glycogen synthase activation in the epididymal adipose tissue from chronic hyperinsulinemic/obese rats

Malathi Srinivasan, Mulchand S. Patel

Journal:

The Journal of Nutritional Biochemistry

Année:

1998

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1998

Purification and Properties of Succinyl-CoA:3-Oxo-Acid CoA-Transferase from Rat Brain

Joseph J. Russell, Mulchand S. Patel

Journal:

Journal of Neurochemistry

Année:

1982

Langue:

english

Fichier:

PDF, 629 KB

english, 1982

Biochemical and structural brain alterations in female mice with cerebral pyruvate dehydrogenase deficiency

Lioudmila Pliss, Roberta J. Pentney, Mark T. Johnson, Mulchand S. Patel

Journal:

Journal of Neurochemistry

Année:

2004

Langue:

english

Fichier:

PDF, 328 KB

english, 2004

Tissue-specific expression of the human pyruvate dehydrogenase α (Pdha-1) / chloramphenicol acetyltransferase fusion gene in transgenic mice

Rama Dey, Sharon Naik, Mulchand S. Patel

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1996

Langue:

english

Fichier:

PDF, 631 KB

english, 1996

Arginine-239 in the beta subunit is at or near the active site of bovine pyruvate dehydrogenase

Devayani Eswaran, M. Showkat Ali, Bhami C. Shenoy, Lioubov G. Korotchkina, Thomas E. Roche, Mulchand S. Patel

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1995

Langue:

english

Fichier:

PDF, 542 KB

english, 1995

Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex

Lioubov G. Korotchkina, Mulchand S. Patel

Journal:

FEBS Letters

Année:

2008

Langue:

english

Fichier:

PDF, 605 KB

english, 2008

Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex

Mulchand S. Patel, Lioubov G. Korotchkina, Sukhdeep Sidhu

Journal:

Journal of Molecular Catalysis B: Enzymatic

Année:

2009

Langue:

english

Fichier:

PDF, 574 KB

english, 2009

Characterization of the regulatory region of the human testis-specific form of the pyruvate dehydrogenase α-subunit (PDHA-2) gene

Utpal Datta, Isaiah D. Wexler, Douglas S. Kerr, Itamar Raz, Mulchand S. Patel

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1999

Langue:

english

Fichier:

PDF, 422 KB

english, 1999

Cloning and characterization of a 5.9 kb promoter region of the human pyruvate dehydrogenase α subunit gene

Jie Tan, Mulchand S Patel

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Année:

1999

Langue:

english

Fichier:

PDF, 832 KB

english, 1999

Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal

Lioubov G Korotchkina, Hsin-Sheng Yang, Oren Tirosh, Lester Packer, Mulchand S Patel

Journal:

Free Radical Biology and Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 339 KB

english, 2001

The inhibitory effects of lipoic compounds on mammalian pyruvate dehydrogenase complex and its catalytic components

Young S Hong, Scott J Jacobia, Lester Packer, Mulchand S Patel

Journal:

Free Radical Biology and Medicine

Année:

1999

Langue:

english

Fichier:

PDF, 196 KB

english, 1999

Characterization of Point Mutations in Patients with Pyruvate Dehydrogenase Deficiency: Role of Methionine-181, Proline-188, and Arginine-349 in the α Subunit

Amporn Tripatara, Lioubov G. Korotchkina, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1999

Langue:

english

Fichier:

PDF, 145 KB

english, 1999

Involvement of α-Cysteine-62 and β-Tryptophan-135 in Human Pyruvate Dehydrogenase Catalysis

Lioubov G. Korotchkina, M. Showkat Ali, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1999

Langue:

english

Fichier:

PDF, 142 KB

english, 1999

Differential Effects of Two Mutations at Arginine-234 in the α Subunit of Human Pyruvate Dehydrogenase

Scott J. Jacobia, Lioubov G. Korotchkina, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

2001

Langue:

english

Fichier:

PDF, 144 KB

english, 2001

Characterization of the Mouse Dihydrolipoamide Dehydrogenase (Dld) Gene: Genomic Structure, Promoter Sequence, and Chromosomal Localization

Mark Johnson, Hsin-Sheng Yang, Gary L. Johanning, Mulchand S. Patel

Journal:

Genomics

Année:

1997

Langue:

english

Fichier:

PDF, 903 KB

english, 1997

Inactivation of the Murine Pyruvate Dehydrogenase (Pdha1) Gene and Its Effect on Early Embryonic Development

Mark T. Johnson, Saleh Mahmood, Susannah L. Hyatt, Hsin-Sheng Yang, Paul D. Soloway, Richard W. Hanson, Mulchand S. Patel

Journal:

Molecular Genetics and Metabolism

Année:

2001

Langue:

english

Fichier:

PDF, 160 KB

english, 2001

Site-Directed Mutagenesis of Human Dihydrolipoamide Dehydrogenase: Role of Lysine-54 and Glutamate-192 in Stabilizing the Thiolate–FAD Intermediate

Te-Chung Liu, Young Soo Hong, Lioubov G. Korotchkina, Nataraj N. Vettakkorumakankav, Mulchand S. Patel

Journal:

Protein Expression and Purification

Année:

1999

Langue:

english

Fichier:

PDF, 306 KB

english, 1999

Regulation of succinyl-CoA:3-oxoacid CoA-transferase in developing rat brain: Responsiveness associated with prenatal but not postnatal hyperketonemia

Peter M. Haney, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1985

Langue:

english

Fichier:

PDF, 825 KB

english, 1985

Induction of succinyl-coenzyme A:3-oxoacid coenzyme A-transferase during differentiation of 3T3-L1 cells

Mahrukh K. Ganapathi, Cindy Raefsky, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1986

Langue:

english

Fichier:

PDF, 688 KB

english, 1986

Precocious induction of hepatic glucokinase and malic enzyme in artificially reared rat pups fed a high-carbohydrate diet

Peter M. Haney, Cindy Raefsky Estrin, Angela Caliendo, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1986

Langue:

english

Fichier:

PDF, 690 KB

english, 1986

Rat liver mitochondria contain two immunologically distinct dihydrolipoamide dehydrogenases

Donna J. Carothers, Cindy Raefsky-Estrin, Gabriel Pons, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

1987

Langue:

english

Fichier:

PDF, 1022 KB

english, 1987

Ochratoxin a decreases the activity of phosphoenolpyruvate carboxykinase and its mRNA content in primary cultures of rat kidney proximal convoluted tubule cells

Thomas J. Thekkumkara, Mulchand S. Patel

Journal:

Biochemical and Biophysical Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 425 KB

english, 1989

Nucleotide sequence of a cDNA for the dihydrolipoamide acetyltransferase component of human pyruvate dehydrogenase complex

Thomas J. Thekkumkara, Lap Ho, Isaiah D. Wexler, Gabriel Pons, Liu Te-Chung, Mulchand S. Patel

Journal:

FEBS Letters

Année:

1988

Langue:

english

Fichier:

PDF, 491 KB

english, 1988

Sequence conservation in the α and β subunits of pyruvate dehydrogenase and its similarity to branched-chain α-keto acid dehydrogenase

Isaiah D. Wexler, Sullia G. Hemalatha, Mulchand S. Patel

Journal:

FEBS Letters

Année:

1991

Langue:

english

Fichier:

PDF, 861 KB

english, 1991

Function of several critical amino acids in human pyruvate dehydrogenase revealed by its structure

Lioubov G. Korotchkina, Ewa M. Ciszak, Mulchand S. Patel

Journal:

Archives of Biochemistry and Biophysics

Année:

2004

Langue:

english

Fichier:

PDF, 3.84 MB

english, 2004

Metabolic programming in the immediate postnatal period

Malathi Srinivasan, Mulchand S. Patel

Journal:

Trends in Endocrinology & Metabolism

Année:

2008

Langue:

english

Fichier:

PDF, 503 KB

english, 2008

Insulin resistance and high TNFα concentrations precede obesity in rats fed high carbohydrate diet during suckling period

Husam Ghanim, Malathi Srinivisan, Ravikumar Aalinkeel, Mulchand S Patel, Paresh Dandona

Journal:

Diabetes Research and Clinical Practice

Année:

2000

Langue:

english

Fichier:

PDF, 143 KB

english, 2000

Characterization of a missense mutation at histidine-44 in a pyruvate dehydrogenase-deficient patient

Scott J Jacobia, Lioubov G Korotchkina, Mulchand S Patel

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2002

Langue:

english

Fichier:

PDF, 307 KB

english, 2002